Quick-edit element tags
You can double click on the opening tag name of a node in the Elements Panel to edit it.
Copy image as data URI
Right click on an image preview within the Resources Panel to copy it as a Data URI (base 64 encoded).
See matching selectors
When you are viewing a selector in the Styles Pane, comma separated selector portions are colored differently depending on whether or not they match the selected DOM node.
Quickly monitor events from the Console Panel
You can log all the events dispatched to an object using the Command Line API method monitorEvents(object [, events]).
Command click to add multiple cursors in the sources panel
Learn how to to multi-cursor editing in the DevTools sources panel.
Better incognito DevTools
Some appearance preferences are now persisted through to incognito windows.
Toggle the DevTools dock state with a keyboard shortcut
Use Cmd + Shift + D to toggle the DevTools dock state between the last two recently used states.
Unfinished network requests
You can use the Is:running Advanced Network Filter to see unfinished network requests (e.g. running requests).
Cut and copy commands
The support for cut and copy commands allows you to programmatically cut and copy selected text to the users clipboard.
DOM Attributes now on the prototype chain
Chrome is becoming in line with the spec. Check your sites if you are assuming the WebKit logic for attribute propagation
Permissions API for the Web
The Permissions API gives you a central place to check the permission status of an API.
Simplified concepts in web animations naming
In response to developer feedback, some upcoming features of Web Animations are being renamed.
A new home for DevTools
We've moved into a shiny new home at developer.google.com/web have great new tutorials and tips for you.
DevTools Timeline - Now providing the full story
We've upgraded the Timeline panel for Chrome DevTools to give developers more insight on their site’s runtime performance.
Creating semantic sites with Web Components and JSON-LD
Add schema.org markup to your components and make them search engine friendly.
Getting Literal With ES6 Template Strings
Template String literals with embedded expressions. We've been waiting for this for ages. Literally